Pigmentary Disorders
نویسنده
چکیده
Many factors have been implicated for the etiology of melasma, but the exact cause of this hypermelanosis is poorly understood. However, it is considered to result from solar radiation and genetic predisposition. Moreover, pregnancy, oral contraception and hormone replacement therapy with natural and synthetic oestrogens, have been involved in the pathogenesis of this hypemelanosis. Despite the fact that melanocytes contain oestrogen receptors that stimulate these cells to become hyperactive, the exact mechanism of estrogens in triggering melasma is unknown [1].
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Increasing our understanding of pigmentary disorders.
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